NEI funded Postdoctoral/Graduate Student Positions available immediately in
The project recognizes the fact that progress in the field of photoreceptor
degeneration and the therapeutic intervention is limited by the need to know
the identities of rescue factors and target genes in the photoreceptors.
Photoreceptor degeneration can be triggered by a variety of genetic and
environmental causes, but all forms appear to lead to photoreceptor
apoptosis. Current therapeutic approaches focus on cytokines, however, none
of which have been found to act directly on the photoreceptors themselves.
This project aims to develop a database on retinal degeneration, using gene
expression arrays. Tissue from mouse various retinal degeneration models,
with and without photoreceptor rescue treatment with neurotrophic factors
will be analyzed and correlation-based analysis will used to reveal common
aspects of signaling both during retinal degeneration and neural protection.
Understanding the molecular mechanisms of action of both of these events
could lead to new therapeutic strategies for the treatment of photoreceptor
Positions are available immediately at the Medical University of South
Carolina in Charleston. Interested Graduate Students would obtain their
degree through the Department of Physiology and Neuroscience. MUSC is close
to the historic district of Charleston, a mid-size city full of charm,
cultural events and water-related recreational opportunities; and the lab is
part of both the newly established Physiology & Neuroscience Department as
well as the Ophthalmology Department, offering close collaborations with
both basic and clinical scientists.
Candidates should have a strong background and interest in retinal biology
and molecular biology. Interested individuals should send a letter stating
their research interested and experience, a CV and names of three references
Bärbel Rohrer, Ph.D.
Storm Eye Institute
Medical University of South Carolina
Departments of Ophthalmology and Physiology & Neuroscience
167 Ashley Ave, Rm 707
Charleston, SC 29425
or to firstname.lastname@example.org
MUSC is an equal opportunity employer.
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