[visionlist] Project in vision - ultra-high channel count neural interfaces in the macaque brain, in Paris

Pieter Roelfsema p.roelfsema at nin.knaw.nl
Mon Sep 23 10:10:10 -04 2024


We have a vacancy for a PhD-student/ Postdoc in the Roelfsema laboratory at the at the Institut de la Vision (IDV) in Paris to develop and test ultra-high channel count neural interfaces in the macaque brain.



The position

The group of Pieter Roelfsema in the Paris lab at the Institut de la Vision (IDV) is seeking a highly motivated researcher. The project aims to explore the function and organization of the visual brain using ultra high channel count neural interfaces in the macaque brain. This research will lead to new discoveries in visual neuroscience and will help toward the larger goal of vision restoration for the blind by interfacing with the brain.



Project description: measuring the activity of neurons across the brain during behavior

The candidate will use high-channel count flexible electrode arrays to measure and change the electrical activity in cortical and subcortical brain regions of macaque monkeys during behavior. The aims of this project are to (1) develop the method for parallel ultra-high channel count electrophysiological recording and stimulation in behaving macaques; (2) to measure the activity of cortical neurons to visual stimuli, behavior and artificial vision (3) to test the influence of brain stimulation methods that ultimately will contribute to brain implants for restoring vision.



Mandatory requirements:

  *   Degree in Neuroscience, Biology, Engineering or equivalent relevant background (Master’s or PhD)
  *   Experience in electrophysiology of neuronal activity in living brain tissue
  *   Strong coding skills
  *   The candidate should be proficient in written and oral English and have experience with writing scientific texts
  *   Personal skills will be emphasized. The candidate should be able to work independently and interactively in a team setting, be motivated and responsible, and have a great work capacity and enthusiasm for research.



The ideal candidate would have additional skills, such as:

  *   Experience in training animals on behavioral tasks
  *   Analysis of large data sets
  *   Hands-on experience in new electrophysiology techniques (Neuropixels, etc)
  *   Experience in other brain recording techniques (electrophysiology, EEG, fMRI, fUS, …)
  *   Surgery and chronic implant management experience



Please contact Florian Fallegger (florian.fallegger at inserm.fr<mailto:florian.fallegger at inserm.fr>). General information about the IDV can be found at  https://sante.sorbonne-universite.fr/en/structures-de-recherche/institut-de-la-vision



For recent relevant publications from the Roelfsema lab, see:

Chen et al., Shape perception via a high-channel-count neuroprosthesis in monkey visual cortex. Science 2020.

Teeuwen et al., A neuronal basis of iconic memory in macaque primary visual cortex, Curr. Biol. 2021.

Roelfsema, Solving the binding problem: assemblies form when neurons enhance their firing rate – they don’t need to oscillate or synchronize. Neuron, 2023.

Papale et al., The representation of occluded image regions in area V1 of monkeys and humans, Curr. Biol. 2023.

Orlemann et al., Flexible polymer electrodes for stable prosthetic visual perception in mice. Adv. Healthcare Mat., 2024.



Applications can be submitted at:

https://www.institut-vision.org/recrutement/phd-ou-post-doc-en-neurosciences-du-systeme-visuel-et-en-protheses






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