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--></style></head><body bgcolor=white lang=EN-US link="#0563C1" vlink="#954F72"><div class=WordSection1><p class=MsoNormal><span style='font-size:11.0pt'>We are looking for a scientist to unravel the relationship between neural dynamics and emergent signals in healthy and diseased brains. Are you passionate about biophysics and the brain? We have massive amounts of simulations and data! (For more details, see the job description below.)<o:p></o:p></span></p><p class=MsoNormal><span style='font-size:11.0pt'><o:p> </o:p></span></p><p class=MsoNormal><span style='font-size:11.0pt'>If you want to apply for this position, you can do so here:<o:p></o:p></span></p><p class=MsoNormal><span style='font-size:11.0pt'><a href="http://www.alleninstitute.org/what-we-do/brain-science/careers/job-search/">http://www.alleninstitute.org/what-we-do/brain-science/careers/job-search/</a><o:p></o:p></span></p><p class=MsoNormal><span style='font-size:11.0pt'>by clicking under position “Scientist I – Biophysical Systems and Signals”.<o:p></o:p></span></p><p class=MsoNormal><span style='font-size:11.0pt'><o:p> </o:p></span></p><p class=MsoNormal><span style='font-size:11.0pt'>Best, Costas<o:p></o:p></span></p><p class=MsoNormal><span style='font-size:11.0pt'>—<o:p></o:p></span></p><p class=MsoNormal><b><span style='font-size:11.0pt'>Costas Anastassiou</span></b><span style='font-size:11.0pt'><o:p></o:p></span></p><p class=MsoNormal><span style='font-size:11.0pt'>Assistant Investigator<o:p></o:p></span></p><p class=MsoNormal><b><span lang=DE style='font-size:11.0pt'>T: </span></b><span lang=DE style='font-size:11.0pt'>206.547.8434<o:p></o:p></span></p><p class=MsoNormal><b><span lang=DE style='font-size:11.0pt'>E: </span></b><b><span style='font-size:11.0pt'><a href="mailto:costasa@alleninstitute.org"><span lang=DE style='font-weight:normal'>costasa@alleninstitute.org</span></a></span></b><span lang=DE style='font-size:11.0pt'><o:p></o:p></span></p><p class=MsoNormal><span lang=DE style='font-size:11.0pt'> <o:p></o:p></span></p><p class=MsoNormal><span style='font-size:11.0pt'><img border=0 width=146 height=34 id="Picture_x0020_2" src="cid:image001.png@01D27018.0C7584C0"></span><span lang=DE style='font-size:11.0pt'> <o:p></o:p></span></p><p class=MsoNormal><span style='font-size:11.0pt'><a href="applewebdata://E6BCC600-823F-44A2-991B-91B98861DCAE/alleninstitute.org">alleninstitute.org</a><o:p></o:p></span></p><p class=MsoNormal><span style='font-size:11.0pt'> <o:p></o:p></span></p><p class=MsoNormal><span style='font-size:11.0pt'>Professor (adj.) of Neurology<o:p></o:p></span></p><p class=MsoNormal><span style='font-size:11.0pt'>University of British Columbia, Vancouver BC, CA<o:p></o:p></span></p><p class=MsoNormal><span style='font-size:11.0pt'><a href="http://neuroscience.ubc.ca/people/Anastassiou">http://neuroscience.ubc.ca/people/Anastassiou</a><o:p></o:p></span></p><div style='mso-element:para-border-div;border:none;border-bottom:double windowtext 2.25pt;padding:0in 0in 1.0pt 0in'><p class=MsoNormal style='border:none;padding:0in'><span style='font-size:11.0pt'><o:p> </o:p></span></p></div><p class=MsoNormal><span style='font-size:11.0pt'>Our mission at the Allen Institute for Brain Science is to accelerate the understanding of how the human brain works in health and disease. By implementing a team science approach on a large scale, we strive to generate useful public resources, drive technological innovations and discover fundamental brain properties through integration of experiments, modeling and theory.<o:p></o:p></span></p><p class=MsoNormal><b><span style='font-size:11.0pt'>POSITION SUMMARY</span></b><span style='font-size:11.0pt'><o:p></o:p></span></p><p class=MsoNormal><span style='font-size:11.0pt'>We are seeking to fill a position at the level of Scientist I to work on the relationship between neural systems, associated signals emerging from neural functioning (such as extracellular recordings, etc.) and reduced representations of such functioning. More specifically, the SciI will (i) design and conduct simulations with an existing large-scale computational model of cortex consisting of a multitude of reconstructed, interconnected and biophysically realistic neurons emulating signals as typically measured in vivo (e.g. [Schomburg, Anastassiou et al, <i>J Neurosci</i>, 2012; Reimann, Anastassiou et al, <i>Neuron</i>, 2013; Taxidis, Anastassiou et al, <i>Neuron</i>, 2015); (ii) analyze simulations to define an effective mapping between neural functioning and measures of neural activity; (iii) compare computational findings with <i>in vivo</i> e-phys recordings (e.g. http://observatory.brain-map.org/visualcoding)<br><br><o:p></o:p></span></p><p class=MsoNormal><b><span style='font-size:11.0pt'>ESSENTIAL DUTIES AND RESPONSIBILITIES</span></b><span style='font-size:11.0pt'><o:p></o:p></span></p><ul style='margin-top:0in' type=disc><li class=MsoNormal style='mso-list:l1 level1 lfo1'><span style='font-size:11.0pt'>Computational modeling of neurons and networks. <o:p></o:p></span></li><li class=MsoNormal style='mso-list:l1 level1 lfo1'><span style='font-size:11.0pt'>Data integration, analyses and visualization.<o:p></o:p></span></li><li class=MsoNormal style='mso-list:l1 level1 lfo1'><span style='font-size:11.0pt'>Integration with ongoing experimental efforts.<o:p></o:p></span></li><li class=MsoNormal style='mso-list:l1 level1 lfo1'><span style='font-size:11.0pt'>Preparation of regular written and oral reports.<o:p></o:p></span></li><li class=MsoNormal style='mso-list:l1 level1 lfo1'><span style='font-size:11.0pt'>Maintain clear and accurate communication with supervisor, team members and external collaborators.<o:p></o:p></span></li><li class=MsoNormal style='mso-list:l1 level1 lfo1'><span style='font-size:11.0pt'> Publish/present findings in peer-reviewed journals/scientific conferences. <br><br><o:p></o:p></span></li></ul><p class=MsoNormal><b><span style='font-size:11.0pt'>QUALIFICATIONS</span></b><span style='font-size:11.0pt'><o:p></o:p></span></p><ul style='margin-top:0in' type=disc><li class=MsoNormal style='mso-list:l0 level1 lfo2'><span style='font-size:11.0pt'>PhD degree in computational neuroscience, physics, applied mathematics, bioengineering, applied mathematics or related field.<o:p></o:p></span></li><li class=MsoNormal style='mso-list:l0 level1 lfo2'><span style='font-size:11.0pt'>Strong background in scientific computing; experience in computational neuroscience is preferred, but other strong applicants will be considered (with background e.g. in computational physics, applied mathematics, biophysics, machine learning and related disciplines). Experience with parallel computing is a plus as well as familiarity with high-level programming languages such as Python.<br><br><o:p></o:p></span></li><li class=MsoNormal style='mso-list:l0 level1 lfo2'><span style='font-size:11.0pt'> Ability to meet aggressive timelines and deliverables in a collaborative environment.<o:p></o:p></span></li><li class=MsoNormal style='mso-list:l0 level1 lfo2'><span style='font-size:11.0pt'> Strong publication record.<o:p></o:p></span></li><li class=MsoNormal style='mso-list:l0 level1 lfo2'><span style='font-size:11.0pt'> Experience in pursuing research projects in collaborative fashion.<o:p></o:p></span></li><li class=MsoNormal style='mso-list:l0 level1 lfo2'><span style='font-size:11.0pt'> Proven independent thinking and flexibility.<o:p></o:p></span></li><li class=MsoNormal style='mso-list:l0 level1 lfo2'><span style='font-size:11.0pt'> Familiarity with <i>in vitro </i>and <i>in vivo </i>electrophysiological monitoring techniques and data analyses.<o:p></o:p></span></li><li class=MsoNormal style='mso-list:l0 level1 lfo2'><span style='font-size:11.0pt'> Strong written and verbal communication skills.<o:p></o:p></span></li></ul><div style='mso-element:para-border-div;border:none;border-bottom:double windowtext 2.25pt;padding:0in 0in 1.0pt 0in'><p class=MsoNormal style='border:none;padding:0in'><span style='font-size:11.0pt'><o:p> </o:p></span></p></div><p class=MsoNormal><span style='font-size:11.0pt'><o:p> </o:p></span></p></div></body></html>