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--></style></head><body bgcolor=white lang=EN-US link="#0563C1" vlink="#954F72"><div class=WordSection1><p class=MsoNormal><span style='font-size:11.0pt'>Dear All:<o:p></o:p></span></p><p class=MsoNormal><span style='font-size:11.0pt'><o:p> </o:p></span></p><p class=MsoNormal><span style='font-size:11.0pt'>We are seeking a Scientist to be an essential team member in our ongoing effort to understand how the <i>human</i> <i>brain</i> processes information. The core responsibility for this position is to setup large-scale computational simulations and data analysis workflows from slice and <i>in vivo</i> brain physiology in humans. Find the full job description attached below.<o:p></o:p></span></p><p class=MsoNormal><span style='font-size:11.0pt'><o:p> </o:p></span></p><p class=MsoNormal><span style='font-size:11.0pt'>To apply for this position, apply through the link below:<o:p></o:p></span></p><p class=MsoNormal><span style='font-size:11.0pt'><a href="https://apply.hrmdirect.com/resumedirect/ApplyOnline/Apply.aspx?req_id=653519&source=653519-CJB-0">https://apply.hrmdirect.com/resumedirect/ApplyOnline/Apply.aspx?req_id=653519&source=653519-CJB-0</a><o:p></o:p></span></p><p class=MsoNormal><span style='font-size:11.0pt'><o:p> </o:p></span></p><p class=MsoNormal><span style='font-size:11.0pt'>Best, Costas<o:p></o:p></span></p><p class=MsoNormal><span style='font-size:11.0pt'><o:p> </o:p></span></p><div style='mso-element:para-border-div;border:none;border-bottom:double windowtext 2.25pt;padding:0in 0in 1.0pt 0in'><p class=MsoNormal style='border:none;padding:0in'><span style='font-size:11.0pt'>--<o:p></o:p></span></p><p class=MsoNormal style='border:none;padding:0in'><b><span style='font-size:11.0pt'>Costas Anastassiou</span></b><span style='font-size:11.0pt'><o:p></o:p></span></p><p class=MsoNormal style='border:none;padding:0in'><span style='font-size:11.0pt'>Assistant Investigator<o:p></o:p></span></p><p class=MsoNormal style='border:none;padding:0in'><b><span lang=DE style='font-size:11.0pt'>T: </span></b><span lang=DE style='font-size:11.0pt'>206.548.8434<o:p></o:p></span></p><p class=MsoNormal style='border:none;padding:0in'><b><span lang=DE style='font-size:11.0pt'>E: </span></b><b><span style='font-size:11.0pt'><a href="mailto:costasa@alleninstitute.org"><span lang=DE style='font-weight:normal'>costasa@alleninstitute.org</span></a></span></b><span lang=DE style='font-size:11.0pt'><o:p></o:p></span></p><p class=MsoNormal style='border:none;padding:0in'><span lang=DE style='font-size:11.0pt'> <o:p></o:p></span></p><p class=MsoNormal style='border:none;padding:0in'><span style='font-size:11.0pt'><img border=0 width=146 height=34 id="_x0000_i1025" src="cid:image001.png@01D36F38.11C23BB0"></span><span lang=DE style='font-size:11.0pt'> <o:p></o:p></span></p><p class=MsoNormal style='border:none;padding:0in'><span style='font-size:11.0pt'><a href="applewebdata://E6BCC600-823F-44A2-991B-91B98861DCAE/alleninstitute.org">alleninstitute.org</a><o:p></o:p></span></p><p class=MsoNormal style='border:none;padding:0in'><span style='font-size:11.0pt'> <o:p></o:p></span></p><p class=MsoNormal style='border:none;padding:0in'><span style='font-size:11.0pt'>Professor (adj.) of Neurology<o:p></o:p></span></p><p class=MsoNormal style='border:none;padding:0in'><span style='font-size:11.0pt'>University of British Columbia, Vancouver BC, CA<o:p></o:p></span></p><p class=MsoNormal style='border:none;padding:0in'><span style='font-size:11.0pt'><a href="http://neuroscience.ubc.ca/people/Anastassiou">http://neuroscience.ubc.ca/people/Anastassiou</a><o:p></o:p></span></p><p class=MsoNormal style='border:none;padding:0in'><span style='font-size:11.0pt'><o:p> </o:p></span></p><p class=MsoNormal style='border:none;padding:0in'><span style='font-size:11.0pt'><o:p> </o:p></span></p></div><p class=MsoNormal><span style='font-size:11.0pt'><o:p> </o:p></span></p><p class=MsoNormal><span style='font-size:11.0pt'>Our mission at the Allen Institute for Brain Science is to accelerate the understanding of how the human brain works in health and disease. By implementing a team science approach on a large scale, we strive to generate useful public resources, drive technological innovations and discover fundamental brain properties through integration of experiments, modeling and theory.<o:p></o:p></span></p><p class=MsoNormal><b><span style='font-size:11.0pt'><o:p> </o:p></span></b></p><p class=MsoNormal><b><span style='font-size:11.0pt'>POSITION SUMMARY</span></b><span style='font-size:11.0pt'><o:p></o:p></span></p><p class=MsoNormal><span style='font-size:11.0pt'>We are seeking a Scientist to be an essential team member in our ongoing effort to understand how the <i>human</i> <i>brain</i> processes information. The core responsibility for this position is to setup large-scale computational simulations and data analysis workflows from slice and <i>in vivo</i> brain physiology in humans. More specifically, the Scientist will (i) design and conduct simulations with an existing large-scale computational framework allowing simulation of a multitude of reconstructed, interconnected and biophysically realistic human neurons (e.g. [Schomburg, Anastassiou et al, <i>J Neurosci</i>, 2012; Reimann, Anastassiou et al, <i>Neuron</i>, 2013]; (ii) analyze simulated and experimental data to establish structure-function relationships (e.g. [Taxidis, Anastassiou et al, <i>Neuron</i>, 2015]); (iii) develop dimensionally reduced representations of neural function (e.g. using machine learning or statistical data modeling) based on recorded signals (encoding) and develop methods for reconstructing neural function from neural activity (decoding); (iv) compare computational findings with experimental observables.<o:p></o:p></span></p><p class=MsoNormal><span style='font-size:11.0pt'><o:p> </o:p></span></p><p class=MsoNormal><b><span style='font-size:11.0pt'>ESSENTIAL DUTIES AND RESPONSIBILITIES</span></b><span style='font-size:11.0pt'><o:p></o:p></span></p><ul style='margin-top:0in' type=disc><li class=MsoNormal style='margin-left:0in;mso-list:l2 level1 lfo1'><span style='font-size:11.0pt'>In close collaboration with theoreticians and experimental colleagues, design, implement and conduct single-neuron and large-scale network simulations of human middle temporal gyrus.<o:p></o:p></span></li><li class=MsoNormal style='margin-left:0in;mso-list:l2 level1 lfo1'><span style='font-size:11.0pt'>Contribute to ongoing efforts in computational framework development (simulation and data analysis) as well as to scientific questions relevant to the system under investigation.<o:p></o:p></span></li><li class=MsoNormal style='margin-left:0in;mso-list:l2 level1 lfo1'><span style='font-size:11.0pt'>Contribute to adjacent projects related to human pathophysiology and neurotherapies.<o:p></o:p></span></li><li class=MsoNormal style='margin-left:0in;mso-list:l2 level1 lfo1'><span style='font-size:11.0pt'>Publish/present findings in peer-reviewed journals/scientific conferences.<o:p></o:p></span></li><li class=MsoNormal style='margin-left:0in;mso-list:l2 level1 lfo1'><span style='font-size:11.0pt'>Prepare written and oral reports on a regular basis.<o:p></o:p></span></li><li class=MsoNormal style='margin-left:0in;mso-list:l2 level1 lfo1'><span style='font-size:11.0pt'>Maintain clear and accurate communication with supervisor, team members and external collaborators.<o:p></o:p></span></li></ul><p class=MsoNormal><b><span style='font-size:11.0pt'><o:p> </o:p></span></b></p><p class=MsoNormal><b><span style='font-size:11.0pt'>BASIC QUALIFICATIONS</span></b><span style='font-size:11.0pt'><o:p></o:p></span></p><ul style='margin-top:0in' type=disc><li class=MsoNormal style='margin-left:0in;mso-list:l0 level1 lfo2'><span style='font-size:11.0pt'>PhD degree in computational neuroscience, physics, applied mathematics, bioengineering or related field.<o:p></o:p></span></li><li class=MsoNormal style='margin-left:0in;mso-list:l0 level1 lfo2'><span style='font-size:11.0pt'>Strong background in scientific computing; experience in computational neuroscience is preferred, but other strong applicants will be considered (with background in computational physics, applied mathematics, biophysics, and related disciplines). Experience with parallel computing is a plus as well as familiarity with high-level programming languages such as Python.<o:p></o:p></span></li><li class=MsoNormal style='margin-left:0in;mso-list:l0 level1 lfo2'><span style='font-size:11.0pt'>Familiarity with <i>in vitro </i>and <i>in vivo </i>electrophysiological monitoring techniques and analysis.<o:p></o:p></span></li></ul><p class=MsoNormal><b><span style='font-size:11.0pt'><o:p> </o:p></span></b></p><p class=MsoNormal><b><span style='font-size:11.0pt'>DESIRED QUALIFICATIONS:</span></b><span style='font-size:11.0pt'><o:p></o:p></span></p><ul style='margin-top:0in' type=disc><li class=MsoNormal style='margin-left:0in;mso-list:l1 level1 lfo3'><span style='font-size:11.0pt'>Ability to meet aggressive timelines and deliverables in a collaborative environment.<o:p></o:p></span></li><li class=MsoNormal style='margin-left:0in;mso-list:l1 level1 lfo3'><span style='font-size:11.0pt'> Strong publication record.<o:p></o:p></span></li><li class=MsoNormal style='margin-left:0in;mso-list:l1 level1 lfo3'><span style='font-size:11.0pt'> Experience in pursuing research projects in collaborative fashion.<o:p></o:p></span></li><li class=MsoNormal style='margin-left:0in;mso-list:l1 level1 lfo3'><span style='font-size:11.0pt'> Proven independent thinking and flexibility.<o:p></o:p></span></li><li class=MsoNormal style='margin-left:0in;mso-list:l1 level1 lfo3'><span style='font-size:11.0pt'> Strong written and verbal communication skills.<o:p></o:p></span></li></ul><p class=MsoNormal><span style='font-size:11.0pt'><o:p> </o:p></span></p><p class=MsoNormal><span style='font-size:11.0pt'><o:p> </o:p></span></p><p class=MsoNormal><span style='font-size:11.0pt'><o:p> </o:p></span></p></div></body></html>