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<p>We seek a highly motivated postdoctoral fellow who will work in a lab at the Friedman Brain Institute of Icahn School of Medicine at Mount Sinai, New York City.<o:p></o:p></p>
<p>Hirofumi Morishita Lab (https://www.morishita-lab.com/) studies cortical mechanisms of perceptual and cognitive development relevant to neurodevelopmental and psychiatric disorders. We take an integrated
<em>in vivo</em> approach, combining molecular, anatomical, electrophysiological, imaging and behavior methodologies using mouse models to address fundamental questions in neuroscience (<em>Science</em> 2010,
<em>PNAS</em> 2013, <em>Biol Psychiary</em> 2015, <em>Journal of Neuroscience</em> 2015, 2016,
<em>Neuron </em>2016<em>, Nature Genetics</em> 2017, 2019).<o:p></o:p></p>
<p><strong>The goal of this position is to identify novel molecular/circuit mechanisms of experience-dependent cortical plasticity using mouse visual system, a premier model of critical period.</strong> Potential project will combine slice patch-clamp recordings
and in vivo electrophysiology with optogenetics, pharmacogenetics, and cell-type specific gain/loss of gene expression through genetic and viral techniques. We have an exciting preliminary data supporting the role of specific molecule/local circuits in regulating
cortical plasticity relevant to Amblyopia, and Alzheimer's Disease. Our research program is currently funded by multiple NIH grants to support exciting research endeavors for a talented postdoc.<o:p></o:p></p>
<p>Icahn School of Medicine at Mount Sinai, located at Manhattan, New York City, offers an outstanding environment for a successful postdoctoral career in Neuroscience (ranked no.1 in Neuroscience for NIH funding). <o:p></o:p></p>
<p> <o:p></o:p></p>
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<p><strong>Qualifications: </strong>PhD in neuroscience or relevant experience required. Past experience in slice electrophysiology is preferred. Experience with molecular biology, rodent in vivo analysis (e.g. stereotaxic surgery, behavior experiments, optogenetics),
programing is a plus. <strong>Special consideration will be given to applicants with experience in slice electrophysiology.</strong><o:p></o:p></p>
<p><strong>Application and required documents:</strong><o:p></o:p></p>
<p>1) Cover letter (including description of research experience, skills, & interests)<o:p></o:p></p>
<p>2) CV<o:p></o:p></p>
<p>3) Names and contact information (email & tel) of 3 references with a brief description of your relationship to each reference.<o:p></o:p></p>
<p>Please send the above information as a single pdf file to <a href="mailto:hirofumi.morishita@mssm.edu">
hirofumi.morishita@mssm.edu</a><o:p></o:p></p>
<p><strong>The PI will attend full period of SFN annual meeting this year and will be available to meet in person with candidates.</strong><o:p></o:p></p>
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<p class="MsoNormal"><span style="font-size:10.0pt">===================================<br>
Hirofumi Morishita, M.D., Ph.D.<br>
Associate Professor<br>
Department of Psychiatry, Neuroscience, and Ophthalmology<br>
Mindich Child Health & Development Institute<br>
Friedman Brain Institute<br>
Icahn School of Medicine at Mount Sinai<br>
One Gustave L. Levy Place, Box 1230<br>
New York, NY 10029<br>
Tel: 212-824-8975 (Office: CSM 9-113)<br>
Email: hirofumi.morishita@mssm.edu<br>
http://www.morishita-lab.com/</span><o:p></o:p></p>
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