<div dir="ltr"><p class="MsoNormal" style="text-align:justify;margin:0cm 0cm 8pt;line-height:107%;font-size:11pt;font-family:Calibri,sans-serif"><span style="font-family:Arial,sans-serif;color:rgb(51,51,51);background-image:initial;background-position:initial;background-size:initial;background-repeat:initial;background-origin:initial;background-clip:initial">There is an exciting Postdoctoral position in the lab of Javier Vargas
in the Department of Optics at the Universidad Complutense de Madrid in Madrid,
Spain to work in the project: “<b>Pushing the computational limits of cryo-EM
to maximize its biomedical impact</b>” supported by Proyectos I+D+I 2019
Modalidad Retos, Ministerio de Ciencia e Innovación. </span></p>

<p class="MsoNormal" style="text-align:justify;margin:0cm 0cm 8pt;line-height:107%;font-size:11pt;font-family:Calibri,sans-serif"><span style="font-family:Arial,sans-serif;color:rgb(51,51,51);background-image:initial;background-position:initial;background-size:initial;background-repeat:initial;background-origin:initial;background-clip:initial">We seek a highly motivated, self-driven and creative thinker who is
prepared to take risks in defining and addressing important scientific
problems, and who is enthusiast about image processing, machine learning and
developing computational approaches in their work.</span></p>

<p class="MsoNormal" style="text-align:justify;margin:0cm 0cm 8pt;line-height:107%;font-size:11pt;font-family:Calibri,sans-serif"><span style="font-family:Arial,sans-serif;color:rgb(51,51,51);background-image:initial;background-position:initial;background-size:initial;background-repeat:initial;background-origin:initial;background-clip:initial">Our work focusses on developing new image processing methods in
cryo-electron microscopy (cryo-EM) to obtain high-resolution 3D reconstructions
of macromolecules as proteins or virus. Cryo-EM is a structural biology
technique that uses the electron microscope to reconstruct biomolecular
assemblies. This technique is living a revolution in its capacity to obtain
atomic-resolution 3D reconstructions of macromolecules. However, the
extraordinary potential of cryo-EM is presently limited by important factors:
several steps in the pipeline can only be performed by highly experienced
researchers, biological complexes are typically conformationally heterogeneous,
and there are not reliable validation methods to evaluate the obtained
structures. Developing algorithms that remove these bottlenecks is critical for
cryo-EM to unfold its tremendous potential as a research tool. Our work aims to
develop these methods to transform cryo-EM into a reliable, high-throughput and
high-resolution technique. We are developers of Cryomethods plugin [1] of
Scipion package [2] and actively collaborate with strong research groups in
Spain [3], Canada [4], United States [5-6] and Mexico [7]. A list of recent
publications can be seen from [8].</span></p>

<p class="MsoNormal" style="text-align:justify;margin:0cm 0cm 8pt;line-height:107%;font-size:11pt;font-family:Calibri,sans-serif"><b><u><span style="font-family:Arial,sans-serif;color:rgb(51,51,51);background-image:initial;background-position:initial;background-size:initial;background-repeat:initial;background-origin:initial;background-clip:initial">Requirements</span></u></b><span style="font-family:Arial,sans-serif;color:rgb(51,51,51);background-image:initial;background-position:initial;background-size:initial;background-repeat:initial;background-origin:initial;background-clip:initial">:</span></p>

<p class="MsoNormal" style="margin:0cm 0cm 6pt;text-align:justify;line-height:107%;font-size:11pt;font-family:Calibri,sans-serif"><span style="font-family:Arial,sans-serif;color:rgb(51,51,51);background-image:initial;background-position:initial;background-size:initial;background-repeat:initial;background-origin:initial;background-clip:initial">- PhD in computer science, physics or computational biology, or a
related field of science.</span></p>

<p class="MsoNormal" style="margin:0cm 0cm 6pt;text-align:justify;line-height:107%;font-size:11pt;font-family:Calibri,sans-serif"><span style="font-family:Arial,sans-serif;color:rgb(51,51,51);background-image:initial;background-position:initial;background-size:initial;background-repeat:initial;background-origin:initial;background-clip:initial">- Previous experience in image processing and data science.</span></p>

<p class="MsoNormal" style="margin:0cm 0cm 6pt;text-align:justify;line-height:107%;font-size:11pt;font-family:Calibri,sans-serif"><span style="font-family:Arial,sans-serif;color:rgb(51,51,51);background-image:initial;background-position:initial;background-size:initial;background-repeat:initial;background-origin:initial;background-clip:initial">- Strong knowledge in Python programming, especially using Numpy,
Matplotlib and Pandas. </span></p>

<p class="MsoNormal" style="margin:0cm 0cm 6pt;text-align:justify;line-height:107%;font-size:11pt;font-family:Calibri,sans-serif"><span style="font-family:Arial,sans-serif;color:rgb(51,51,51);background-image:initial;background-position:initial;background-size:initial;background-repeat:initial;background-origin:initial;background-clip:initial">- Experience working in Linux environments.</span></p>

<p class="MsoNormal" style="margin:0cm 0cm 6pt;text-align:justify;line-height:107%;font-size:11pt;font-family:Calibri,sans-serif"><span style="font-family:Arial,sans-serif;color:rgb(51,51,51);background-image:initial;background-position:initial;background-size:initial;background-repeat:initial;background-origin:initial;background-clip:initial">- Previous experience in machine learning/deep learning.</span></p>

<p class="MsoNormal" style="text-align:justify;margin:0cm 0cm 8pt;line-height:107%;font-size:11pt;font-family:Calibri,sans-serif"><span style="font-family:Arial,sans-serif;color:rgb(51,51,51);background-image:initial;background-position:initial;background-size:initial;background-repeat:initial;background-origin:initial;background-clip:initial">- Good written and oral communication skills in English.</span></p>

<p class="MsoNormal" style="text-align:justify;margin:0cm 0cm 8pt;line-height:107%;font-size:11pt;font-family:Calibri,sans-serif"><span style="font-family:Arial,sans-serif;color:rgb(51,51,51);background-image:initial;background-position:initial;background-size:initial;background-repeat:initial;background-origin:initial;background-clip:initial">Previous experience developing image processing methods in single
particle cryo-EM or cryo-ET and knowledge of Spanish language is a plus.</span></p>

<p class="MsoNormal" style="text-align:justify;margin:0cm 0cm 8pt;line-height:107%;font-size:11pt;font-family:Calibri,sans-serif"><span style="font-family:Arial,sans-serif;color:rgb(51,51,51);background-image:initial;background-position:initial;background-size:initial;background-repeat:initial;background-origin:initial;background-clip:initial">Applicants should submit a CV, a motivation letter outlining research
experiences and interests and two reference letters to Javier Vargas at </span><a href="mailto:jvargas@ucm.es" style="color:rgb(5,99,193)"><b><span style="font-family:Arial,sans-serif;color:black;background-image:initial;background-position:initial;background-size:initial;background-repeat:initial;background-origin:initial;background-clip:initial">jvargas@ucm.es</span></b></a><span style="font-family:Arial,sans-serif;color:black;background-image:initial;background-position:initial;background-size:initial;background-repeat:initial;background-origin:initial;background-clip:initial">   </span><span style="font-family:Arial,sans-serif;color:rgb(51,51,51);background-image:initial;background-position:initial;background-size:initial;background-repeat:initial;background-origin:initial;background-clip:initial"></span></p>

<p class="MsoNormal" style="margin:0cm 0cm 6pt;text-align:justify;line-height:107%;font-size:11pt;font-family:Calibri,sans-serif"><span style="font-family:Arial,sans-serif;color:rgb(51,51,51);background-image:initial;background-position:initial;background-size:initial;background-repeat:initial;background-origin:initial;background-clip:initial">[1] </span><a href="https://github.com/mcgill-femr/scipion-em-cryomethods" style="color:rgb(5,99,193)"><span style="font-family:Arial,sans-serif;background-image:initial;background-position:initial;background-size:initial;background-repeat:initial;background-origin:initial;background-clip:initial">https://github.com/mcgill-femr/scipion-em-cryomethods</span></a><span style="font-family:Arial,sans-serif;color:rgb(51,51,51);background-image:initial;background-position:initial;background-size:initial;background-repeat:initial;background-origin:initial;background-clip:initial"></span></p>

<p class="MsoNormal" style="margin:0cm 0cm 6pt;text-align:justify;line-height:107%;font-size:11pt;font-family:Calibri,sans-serif"><span style="font-family:Arial,sans-serif;color:rgb(51,51,51);background-image:initial;background-position:initial;background-size:initial;background-repeat:initial;background-origin:initial;background-clip:initial">[2] </span><a href="http://scipion.i2pc.es/" style="color:rgb(5,99,193)"><span style="font-family:Arial,sans-serif;background-image:initial;background-position:initial;background-size:initial;background-repeat:initial;background-origin:initial;background-clip:initial">http://scipion.i2pc.es/</span></a><span class="gmail-MsoHyperlink" style="color:rgb(5,99,193);text-decoration-line:underline"></span></p>

<p class="MsoNormal" style="margin:0cm 0cm 6pt;text-align:justify;line-height:107%;font-size:11pt;font-family:Calibri,sans-serif"><span style="font-family:Arial,sans-serif;color:rgb(51,51,51);background-image:initial;background-position:initial;background-size:initial;background-repeat:initial;background-origin:initial;background-clip:initial">[3] </span><a href="http://i2pc.es/about-i2pc/" style="color:rgb(5,99,193)"><span style="font-family:Arial,sans-serif;background-image:initial;background-position:initial;background-size:initial;background-repeat:initial;background-origin:initial;background-clip:initial">http://i2pc.es/about-i2pc/</span></a><span style="font-family:Arial,sans-serif;color:rgb(51,51,51);background-image:initial;background-position:initial;background-size:initial;background-repeat:initial;background-origin:initial;background-clip:initial"></span></p>

<p class="MsoNormal" style="margin:0cm 0cm 6pt;text-align:justify;line-height:107%;font-size:11pt;font-family:Calibri,sans-serif"><span style="font-family:Arial,sans-serif;color:rgb(51,51,51);background-image:initial;background-position:initial;background-size:initial;background-repeat:initial;background-origin:initial;background-clip:initial">[4] </span><a href="https://www.huy-bui.lab.mcgill.ca/" style="color:rgb(5,99,193)"><span style="font-family:Arial,sans-serif;background-image:initial;background-position:initial;background-size:initial;background-repeat:initial;background-origin:initial;background-clip:initial">https://www.huy-bui.lab.mcgill.ca/</span></a><span style="font-family:Arial,sans-serif;color:rgb(51,51,51);background-image:initial;background-position:initial;background-size:initial;background-repeat:initial;background-origin:initial;background-clip:initial"> </span></p>

<p class="MsoNormal" style="margin:0cm 0cm 6pt;text-align:justify;line-height:107%;font-size:11pt;font-family:Calibri,sans-serif"><span style="font-family:Arial,sans-serif;color:rgb(51,51,51);background-image:initial;background-position:initial;background-size:initial;background-repeat:initial;background-origin:initial;background-clip:initial">[5] </span><a href="https://www.mclellanlab.org/lab-members" style="color:rgb(5,99,193)"><span style="font-family:Arial,sans-serif;background-image:initial;background-position:initial;background-size:initial;background-repeat:initial;background-origin:initial;background-clip:initial">https://www.mclellanlab.org/lab-members</span></a><span style="font-family:Arial,sans-serif;color:rgb(51,51,51);background-image:initial;background-position:initial;background-size:initial;background-repeat:initial;background-origin:initial;background-clip:initial"> </span></p>

<p class="MsoNormal" style="margin:0cm 0cm 6pt;text-align:justify;line-height:107%;font-size:11pt;font-family:Calibri,sans-serif"><span style="font-family:Arial,sans-serif;color:rgb(51,51,51);background-image:initial;background-position:initial;background-size:initial;background-repeat:initial;background-origin:initial;background-clip:initial">[6] </span><a href="https://sites.google.com/uw.edu/dais-uw" style="color:rgb(5,99,193)"><span style="font-family:Arial,sans-serif;background-image:initial;background-position:initial;background-size:initial;background-repeat:initial;background-origin:initial;background-clip:initial">https://sites.google.com/uw.edu/dais-uw</span></a><span style="font-family:Arial,sans-serif;color:rgb(51,51,51);background-image:initial;background-position:initial;background-size:initial;background-repeat:initial;background-origin:initial;background-clip:initial"> </span></p>

<p class="MsoNormal" style="margin:0cm 0cm 6pt;text-align:justify;line-height:107%;font-size:11pt;font-family:Calibri,sans-serif"><span style="font-family:Arial,sans-serif;color:rgb(51,51,51);background-image:initial;background-position:initial;background-size:initial;background-repeat:initial;background-origin:initial;background-clip:initial">[7] </span><a href="http://personal.cimat.mx:8181/~julio/" style="color:rgb(5,99,193)"><span style="font-family:Arial,sans-serif;background-image:initial;background-position:initial;background-size:initial;background-repeat:initial;background-origin:initial;background-clip:initial">http://personal.cimat.mx:8181/~julio/</span></a><span style="font-family:Arial,sans-serif;color:rgb(51,51,51);background-image:initial;background-position:initial;background-size:initial;background-repeat:initial;background-origin:initial;background-clip:initial"></span></p>

<p class="MsoNormal" style="margin:0cm 0cm 6pt;text-align:justify;line-height:107%;font-size:11pt;font-family:Calibri,sans-serif"><span style="font-family:Arial,sans-serif;color:rgb(51,51,51);background-image:initial;background-position:initial;background-size:initial;background-repeat:initial;background-origin:initial;background-clip:initial">[8] </span><a href="https://orcid.org/0000-0001-7519-6106" style="color:rgb(5,99,193)"><span style="font-family:Arial,sans-serif;background-image:initial;background-position:initial;background-size:initial;background-repeat:initial;background-origin:initial;background-clip:initial">https://orcid.org/0000-0001-7519-6106</span></a><span style="font-family:Arial,sans-serif;color:rgb(51,51,51);background-image:initial;background-position:initial;background-size:initial;background-repeat:initial;background-origin:initial;background-clip:initial"> </span></p></div>