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<p class="MsoNormal"><span lang="EN-US">The retinal signal processing group has a great opportunity for a: Senior Researcher/Researcher in Visual Neuroscience<o:p></o:p></span></p>
<p class="MsoNormal"><span lang="EN-US"><o:p> </o:p></span></p>
<p class="MsoNormal"><span lang="EN-US">Have you always been fascinated by the visual system? Are you interested in basic neuroscience research, and solving complex problems that may lead to clinically relevant solutions? Are you interested in working in a
multidisciplinary, highly collaborative research group? Do you want to contribute to an ambitious project at the cutting edge of the field? This position may be perfect for you.<o:p></o:p></span></p>
<p class="MsoNormal"><span lang="EN-US"><o:p> </o:p></span></p>
<p class="MsoNormal"><span lang="EN-US">Project description<o:p></o:p></span></p>
<p class="MsoNormal"><span lang="EN-US">Vision is our main sensory input, on which we depend strongly in our daily lives. When vision is malfunctioning, the quality of life reduces enormously. One important aspect of vision is the control of eye movements by
the oculomotor system. If this system malfunctions, nystagmus (oscillating small amplitude eye movements) occur and vision will be strongly impaired. Finding the cause of the nystagmus is therefore not only of high scientific interest but also of great clinical
and societal relevance.<o:p></o:p></span></p>
<p class="MsoNormal"><span lang="EN-US"><o:p> </o:p></span></p>
<p class="MsoNormal"><span lang="EN-US">A new ambitious collaborative project of the Kamermans and the De Zeeuw labs studies the cause of nystagmus and the related reduced visual acuity. We recently showed that infantile nystagmus has a retinal origin (Winkelman
et al., Plos Biology, 2019; <a href="http://www.kamermans.net/nystagmus.mp4">www.kamermans.net/nystagmus.mp4</a>). This discovery led to a paradigm shift in the field. What we do not know is how nystagmus develops, what the cause is of the reduced visual acuity
and how we can cure nystagmus and the visual acuity loss. To fill this gap we will use mouse models where we can genetically manipulate the retinal mechanism inducing infantile nystagmus. We will measure eye-movements, neuronal activity in the retina and the
brain in various developmental stages and use behavioral test to determine the visual acuity of the mice.<o:p></o:p></span></p>
<p class="MsoNormal"><span lang="EN-US"><o:p></o:p></span></p>
<p class="MsoNormal"><span lang="EN-US"><o:p> </o:p></span></p>
<p class="MsoNormal"><span lang="EN-US">You are:<o:p></o:p></span></p>
<p class="MsoNormal"><span lang="EN-US">An ambitious, highly motivated scientist with a PhD in neuroscience, medicine, (bio)physics or related fields and a few years of experience in recording single unit activity either electrophysiologically or by means of
Ca-imaging in mouse brains. Preferably you have experience with behavioral assays with mice as well. Programming skills - in particular with Matlab or Python - will be very useful. Knowledge of the visual system and especially the retina is highly appreciated.
You are a team player and comfortable communicating, presenting and writing in English.<o:p></o:p></span></p>
<p class="MsoNormal"><span lang="EN-US"><o:p> </o:p></span></p>
<p class="MsoNormal"><span lang="EN-US">We offer:<o:p></o:p></span></p>
<p class="MsoNormal"><span lang="EN-US">State of the art infrastructure.<o:p></o:p></span></p>
<p class="MsoNormal"><span lang="EN-US">Excellent technical support.<o:p></o:p></span></p>
<p class="MsoNormal"><span lang="EN-US">A stimulating, international, strongly multidisciplinary and collaborative research environment.<o:p></o:p></span></p>
<p class="MsoNormal"><span lang="EN-US"><o:p></o:p></span></p>
<p class="MsoNormal"><span lang="EN-US">The environment<o:p></o:p></span></p>
<p class="MsoNormal"><span lang="EN-US">The Netherlands Institute for Neuroscience (<a href="http://www.nin.nl">www.nin.nl</a>) is the country’s leading fundamental neuroscience research institute in the international and progressive city of Amsterdam. It provides
a critical mass of scientists (spanning more than 27 nationalities) and neuroscience facilities, in a highly interactive, dynamic, multi-cultural environment, with English as the working language.<o:p></o:p></span></p>
<p class="MsoNormal"><span lang="EN-US"><o:p> </o:p></span></p>
<p class="MsoNormal"><span lang="EN-US">Appointment<o:p></o:p></span></p>
<p class="MsoNormal"><span lang="EN-US">A position is for a period of 3 years. The first appointment is for one year with the option for an extension for the remaining period pending on an evaluation. Because of the upcoming the retirement of Prof. Dr. Kamermans,
active support will be given to the candidate for the acquisition of additional grants to ensure continuation of this exciting research line.<o:p></o:p></span></p>
<p class="MsoNormal"><span lang="EN-US">Depending on education and relevant work experience, the gross monthly salary based on full-time employment varies between € 3413,- and € 4.670,- gross per month (salary scale 10), in accordance with the Collective Labour
Agreement for Dutch Universities (CAO NU), excluding 8% holiday allowance and 8.3% end-of-year bonus. We offer travel expenses, paid parental leave, flexible working hours, 30 days paid leave per year and help by finding a house.<o:p></o:p></span></p>
<p class="MsoNormal"><span lang="EN-US">For more information; <a href="https://nin.nl/research/researchgroups/kamermans-group/">
https://nin.nl/research/researchgroups/kamermans-group/</a> , <a href="http://www.kamermans.net/nystagmus.mp4">
www.kamermans.net/nystagmus.mp4</a> or call Dr. M. Kamermans Phone: +31 20 5665180 or E-mail:
<a href="mailto:m.kamermans@nin.knaw.nl">m.kamermans@nin.knaw.nl</a><o:p></o:p></span></p>
<p class="MsoNormal"><span lang="EN-US"><o:p> </o:p></span></p>
<p class="MsoNormal"><span lang="EN-US">How to apply<o:p></o:p></span></p>
<p class="MsoNormal"><span lang="EN-US">Please submit your application by 1 November 2022.<o:p></o:p></span></p>
<p class="MsoNormal"><span lang="EN-US">Please use the following link: <a href="https://vacatures.knaw.nl/job/Amsterdam-Senior-ResearcherResearcher-in-visual-neuroscience/848363755/">
https://vacatures.knaw.nl/job/Amsterdam-Senior-ResearcherResearcher-in-visual-neuroscience/848363755/</a><o:p></o:p></span></p>
<p class="MsoNormal"><span lang="EN-US">- A curriculum vitae including two letters of reference and<o:p></o:p></span></p>
<p class="MsoNormal"><span lang="EN-US">- One cover letter<o:p></o:p></span></p>
<p class="MsoNormal"><span lang="EN-US">The evaluation of candidates starts immediately and continues until the position is filled.<o:p></o:p></span></p>
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