<div dir="ltr"><div id="gmail-:2i2" class="gmail-Ar gmail-Au gmail-Ao"><div id="gmail-:2hy" class="gmail-Am gmail-Al editable gmail-LW-avf gmail-tS-tW gmail-tS-tY" aria-label="Message Body" role="textbox" aria-multiline="true" tabindex="1" style="direction:ltr;min-height:376px" aria-controls=":2kt" aria-expanded="false"><div><span style="font-family:arial,sans-serif;font-size:12pt">Dear colleagues,</span><br></div><div><p class="MsoNormal" style="line-height:normal;margin:0in 0in 8pt;font-size:11pt"><span style="font-size:12pt"><font face="arial, sans-serif"><br></font></span></p><p class="MsoNormal" style="line-height:normal;margin:0in 0in 8pt;font-size:11pt"><span style="font-size:12pt"><font face="arial, sans-serif">We
are looking for a post-doc for an NIH sponsored project on the role of
functional hyperemia in proper neural function. </font></span></p>
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<p class="MsoNormal" style="line-height:normal;margin:0in 0in 8pt;font-size:11pt"><span style="font-size:12pt"><font face="arial, sans-serif">It
has long been surmised that functional hyperemia (the increase in blood
following neuronal activation) provides oxygen and other metabolic
substrates needed to sustain active neural tissue. However theoretical work has called
this assumption into question.</font></span></p>
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<p class="MsoNormal" style="line-height:normal;margin:0in 0in 8pt;font-size:11pt"><span style="font-size:12pt"><font face="arial, sans-serif">This
project will use state-of-the-art optogenetic techniques to block functional
hyperemia (see our recent pub <a href="https://elifesciences.org/articles/72802" style="color:rgb(5,99,193)">https://elifesciences.org/articles/72802</a>)
while monitoring blood flow, neural activity, and various metabolic substrates
in neurons, astrocytes, and the intercellular space using two-photon imaging,
electrophysiological recordings and metabolic sensors. </font></span></p>
<p class="MsoNormal" style="line-height:normal;margin:0in 0in 8pt;font-size:11pt"><span style="font-size:12pt"><font face="arial, sans-serif"> </font></span></p>
<p class="MsoNormal" style="line-height:normal;margin:0in 0in 8pt;font-size:11pt"><span style="font-size:12pt"><font face="arial, sans-serif">We
seek to determine:</font></span></p>
<p class="gmail-MsoListParagraphCxSpFirst" style="margin:0in 0in 0in 0.75in;line-height:normal;font-size:11pt"><font face="arial, sans-serif"><span style="font-size:12pt">1.<span style="font-variant-numeric:normal;font-variant-east-asian:normal;font-variant-alternates:normal;font-kerning:auto;font-feature-settings:normal;font-stretch:normal;font-size:7pt;line-height:normal">
</span></span><span style="font-size:12pt">How neural responses to visual
stimuli are affected by the loss of functional hyperemia. </span></font></p>
<p class="gmail-MsoListParagraphCxSpLast" style="margin:0in 0in 8pt 0.75in;line-height:normal;font-size:11pt"><font face="arial, sans-serif"><span style="font-size:12pt">2.<span style="font-variant-numeric:normal;font-variant-east-asian:normal;font-variant-alternates:normal;font-kerning:auto;font-feature-settings:normal;font-stretch:normal;font-size:7pt;line-height:normal">
</span></span><span style="font-size:12pt">If the metabolic function of the
neurovascular unit is altered.</span></font></p><p class="gmail-MsoListParagraphCxSpLast" style="margin:0in 0in 8pt 0.75in;line-height:normal;font-size:11pt"><span style="font-size:12pt"><font face="arial, sans-serif"><br></font></span></p></div><div><p class="gmail-MsoListParagraphCxSpFirst" style="line-height:normal;margin:0in 0in 0in 0.5in;font-size:11pt"></p><ul><li><span style="font-family:arial,sans-serif;font-size:12pt">For more information about the lab of
Dr. Philip O’Herron, see </span><a href="https://www.augusta.edu/mcg/phy/faculty/phys_faculty_oherron.php" style="font-size:11pt;font-family:arial,sans-serif;color:rgb(5,99,193)"><span style="font-size:12pt">https://www.augusta.edu/mcg/phy/faculty/phys_faculty_oherron.php</span></a></li></ul><span style="font-size:12pt"><font face="arial, sans-serif"><ul><li><span style="font-size:12pt">If interested, please contact Dr. Philip
O’Herron at </span><a href="mailto:poherron@augusta.edu" style="font-size:11pt;color:rgb(5,99,193)"><span style="font-size:12pt">poherron@augusta.edu</span></a><span style="font-size:12pt">.</span></li></ul></font></span><p></p>
<p class="MsoNormal" align="center" style="text-align:center;line-height:normal;margin:0in 0in 8pt;font-size:11pt"><font face="arial, sans-serif"><i>Explore
and experience Augusta, Georgia: </i><i><span style="font-size:10pt"><a href="https://www.augusta.edu/augusta/" style="color:rgb(5,99,193)"><span style="font-size:11pt">https://www.augusta.edu/augusta/</span></a></span></i><span style="font-size:12pt"></span></font></p>
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<p class="MsoNormal" style="line-height:normal;margin:0in 0in 8pt;font-size:11pt"><span style="font-size:12pt"><font face="arial, sans-serif">Thank you,</font></span></p><p class="MsoNormal" style="line-height:normal;margin:0in 0in 8pt;font-size:11pt"><span style="font-size:12pt"><font face="arial, sans-serif">Philip O'Herron</font></span></p><p class="MsoNormal" style="line-height:normal;margin:0in 0in 8pt"><font face="arial, sans-serif" size="1">Assistant Professor</font></p><p class="MsoNormal" style="line-height:normal;margin:0in 0in 8pt"><font face="arial, sans-serif" size="1">Department of Physiology</font></p><p class="MsoNormal" style="line-height:normal;margin:0in 0in 8pt"><font face="arial, sans-serif" size="1">Augusta University</font></p><p class="MsoNormal" style="line-height:normal;margin:0in 0in 8pt"><font face="arial, sans-serif" size="1">Augusta GA, USA</font></p>
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