[visionlist] Post Doctoral fellowship to work on animal-based myopia research

[Christine Wildsoet]

Job opportunities: Post Doctoral fellowship to work on animal-based research into eye growth regulation and myopia, and role of sex hormones, with optical, molecular, physiological and biomechanical tools applied to understand underlying mechanisms and develop novel treatment options.  
The UC Berkeley Myopia Research group is involved in multidisciplinary basic and applied research, involving cell and tissue cultures, two animal models (chicks and guinea pigs) and human subjects. We have on-going collaborations both within and outside University of California Berkeley and our publications appear in a variety of vision journals, including Investigative Ophthalmology Visual Science. 

Two post docs are sought to join on-going projects, one of which seeks to address the question of why human females appear to be more susceptible to myopia than males. Specifically, the chick form deprivation model of myopia is being used to investigate the role of local and circulating sex hormones in eye growth regulation, with the ocular sclera being the principal focus of our investigations. LC-MS/MS, real time PCR, western blotting and immunohistochemistry are being used as tools in our investigations. The main focus of the second project, which makes use of the guinea pig model, is the effects of IOP lowering drugs on myopia progression, as an extension of our recent published study involving latanoprost. Initial appointments will be for 12 months, with the potential to extend, funding permitting.

Requirements:
- Highly motivated and good team player.
- PhD degree with biological emphasis (sex hormone project), or ocular focus with some clinical experience (IOP-myopia control project).
- Excellent publication track records . 
- Experience with real-time PCR, western blotting and basis histology essential; experience with working with small animal models, LC-MS/MS and micro-dissection preferable (sex hormone project).
- Experience with clinical and functional ocular evaluations, such as ocular biometry, multifocal ergs and high resolution OCT imaging essential; experience with small animal models desirable.

Application instructions:
Please send your CV, accompanied by a cover letter, which includes the name and contact information of at least one reference writer, to wildsoet at berkeley.edu <mailto:martin.humenberger at naverlabs.com>.

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Prof Christine Wildsoet  OD, PhD, FAAO, FARVO
UC Berkeley Myopia Research Group
School of Optometry, 588 Minor Hall
University of California
Berkeley CA 94720-2020
Phone: 510-643-4472
http://wildsoetlab.berkeley.edu
Never regret anything that has happened in your life; it cannot be changed, undone or forgotten so take it as a lesson learned and move on.
Have patience with all things; but first of all with yourself.






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